If this error ocurred it is recommended to check whether your Zend Optimizer is installed correctly. To test it you can create a small script file like test.php that contains:
<?php phpinfo(); ?>
and look at the result output of the function. Then search for the section named 'Zend Optimizer' which contains listing of some Zend variables and their settings. If it doesn't exists it means that Zend Optimizer is not installed.
Also, make sure that you have installed a compatible version of Zend Optimizer. We would recommend 2.6.2 version for PHP 4 and 3.2 version for PHP 5.